Mouth Sores are like little cuts or ulcers in the mouth. The lesion may be very red, or may have small white patches in the middle.
They may bleed or become infected. There are various causes of these mouth sores and TKI drug might be one of those.
When should I call my doctor?
Call the poziotinib study team opon first appearance of these sores.
Take these steps:
Check your mouth twice a day using a small flashlight and a padded popsicle stick. If you wear dentures, take them out before you check your mouth.
Follow the plan below for mouth care 30 minutes after eating and every 4 hours while you’re awake, or at least twice a day unless you’ve been given other instructions:
Brush your teeth using a soft nylon bristle toothbrush. To soften the bristles even more, soak the brush in hot water beforehand and rinse it with hot water during brushing. If the toothbrush hurts, use a popsicle stick with gauze wrapped around it.
Get soft foam mouth swabs to clean your teeth. (You can buy these at a drugstore)
Use a non-abrasive toothpaste that contains fluoride.
Choose foods that are soft, wet, and easy to swallow. When your mouth is sore, try cooked cereals, mashed potatoes, and scrambled eggs.
Avoid drinking orange, lemon, tomato, or grapefruit juice and alcoholic drinks. Avoid spicy foods or food or drinks that have sugar in them such as candy and soft drinks.
Poziotinib is an investigational drug that has not been approved by the FDA.